Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | IL6ST | P40189 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC3R | P41968 | 2/20 | 0.40 |
| ▸ | MC1R | Q01726 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522276 | 1.00 | NAAA (0.51) | NAAALMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23866771 | 1.00 | NAAA (0.51) | NAAALMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1915646 | 0.92 | NAAA (0.47) | NAAAALDH1A1HPGDIL6STFAAH | |
| SCHEMBL1915643 | 0.92 | NAAA (0.47) | NAAAALDH1A1HPGDIL6STFAAH | |
| SCHEMBL7346791 | 0.92 | NAAA (0.47) | NAAAALDH1A1HPGDIL6STFAAH | |
| SCHEMBL23736402 | 0.88 | NAAA (0.54) | NAAALMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16594226 | 0.88 | NAAA (0.60) | NAAAFAAHTDP1L3MBTL1CASP3 | |
| SCHEMBL16594224 | 0.88 | NAAA (0.60) | NAAAFAAHTDP1L3MBTL1CASP3 | |
| SCHEMBL16680346 | 0.88 | CACNA1G (0.43) | NAAAALDH1A1IL6STFAAHPKM | |
| SCHEMBL21871072 | 0.88 | NAAA (0.42) | NAAAIL6STFAAHMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731962-B2 | LpxC inhibitor and methods of making | BLACKSMITH MEDICINES, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11731962-B2 | LpxC inhibitor and methods of making | BLACKSMITH MEDICINES, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20210309651-A1 | LPXC INHIBITOR AND METHODS OF MAKING | BLACKSMITH MEDICINES, INC. | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731962-B2 | LpxC inhibitor and methods of making | LPXN, LCT, AGXT | NAAA 63/4885LMNA 327/4885SMN1; SMN2 4600/4885 |
| US-20210309651-A1 | LPXC INHIBITOR AND METHODS OF MAKING | LPXN, LCT, AGXT | NAAA 63/4885LMNA 327/4885SMN1; SMN2 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.