Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.52 |
| ▸ | GFER | P55789 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | RORC | P51449 | 9/20 | 0.51 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373787 | 1.00 | GAA (0.52) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL2373794 | 0.90 | L3MBTL1 (0.45) | MAPTGFERRORCPOLBSMN1; SMN2 | |
| SCHEMBL2373800 | 0.90 | L3MBTL1 (0.45) | MAPTGFERRORCPOLBSMN1; SMN2 | |
| SCHEMBL15809910 | 0.85 | MAPK1 (0.55) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL15809911 | 0.85 | MAPK1 (0.55) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL15810069 | 0.83 | MAPK1 (0.49) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL15810067 | 0.83 | MAPK1 (0.49) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL15810002 | 0.81 | L3MBTL1 (0.53) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL15810003 | 0.81 | L3MBTL1 (0.53) | GAAMAPTALOX15ALOX12GFER | |
| SCHEMBL2373494 | 0.81 | GPR142 (0.44) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | CTSA, BECN1, HDAC6 | GAA 625/4885MAPT 316/4885ALOX15 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.