⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321693 | 0.73 | — | — | |
| SCHEMBL1867172 | 0.69 | KDM4E (0.39) | — | |
| SCHEMBL23736349 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL28320583 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL8043338 | 0.67 | — | — | |
| SCHEMBL3439738 | 0.66 | — | — | |
| SCHEMBL153237 | 0.65 | — | — | |
| Acetamide SCHEMBL6158507 | 0.65 | LMNA (0.47) | — | |
| SCHEMBL498258 | 0.63 | — | — | |
| SCHEMBL437859 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| EP-3862023-A1 | CONJUGATES OF CELL-BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou DAC Biotech Co, Ltd (CN) | 2021-08-11 | — | — | EP | disclosed |