Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345120 | 1.00 | MEN1 (0.61) | MEN1KMT2ATDP1ALDH1A1ATM | |
| SCHEMBL19125533 | 0.79 | TP53 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL26287659 | 0.79 | NPSR1 (0.47) | MEN1KMT2ATDP1ALDH1A1ATM | |
| SCHEMBL12858036 | 0.79 | MEN1 (0.38) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5078316 | 0.79 | MEN1 (0.59) | MEN1KMT2ATDP1ALDH1A1ATM | |
| SCHEMBL28012847 | 0.78 | MEN1 (0.37) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13313461 | 0.78 | HPGD (0.46) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL9423230 | 0.77 | ALDH1A1 (0.67) | MEN1KMT2ATDP1ALDH1A1MAPK1 | |
| SCHEMBL630361 | 0.76 | KMT2A (0.36) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27730537 | 0.76 | KMT2A (0.36) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431096-B1 | GLUCOCORTICOID COMBINED WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN-2 FOR TREATING RESPIRATORY DISEASE | XIE YANHUI (CN) | 2024-12-18 | — | — | EP | claimed |
| EP-3840769-B1 | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE | BACAINN BIOTHERAPEUTICS LTD (KY) | 2024-07-24 | — | — | EP | claimed |
| EP-2643002-B1 | PHARMACEUTICAL FORMULATIONS CONTAINING CORTICOSTEROIDS FOR TOPICAL ADMINISTRATION | BAUSCH HEALTH IRELAND LTD (IE) | 2023-01-04 | — | — | EP | claimed |
| EP-4149929-B1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AG (DE) | 2026-01-28 | — | — | EP | disclosed |
| US-12520844-B2 | Triazine and pyrimidine (thio)amides as fungicidal compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-13 | — | — | US | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230180756-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-15 | — | — | US | disclosed |
| EP-4149929-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2023-03-22 | — | — | EP | disclosed |
| CN-115605462-A | Triazine and pyrimidine (thio) amides as fungicidal compounds | 拜耳公司（DE） | 2023-01-13 | — | — | CN | disclosed |
| WO-2021228734-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-11-18 | — | — | WO | disclosed |
| EP-3204383-B1 | SPIRODIAMINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2020-11-18 | — | — | EP | disclosed |
| CN-102791714-A | N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as PDE10A inhibitors | HOFFMANN LA ROCHE | 2012-11-21 | — | — | CN | disclosed |
| US-20110237564-A1 | IMIDAZOPYRIMIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2011-09-29 | — | — | US | disclosed |
| WO-2011117264-A1 | N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-09-29 | — | — | WO | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| EP-0497851-B1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-04 | — | — | EP | disclosed |
| US-5324710-A | Sulfonated heterocyclic carboxamides and their use as herbicides, and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0497851-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES. | HOECHST AG (DE) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006541-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230180756-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | TPMT, TYMP, TPI1 | MEN1 4691/4885KMT2A 1688/4885TDP1 447/4885 |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CDK1, CDKN1A, CDKL1 | MEN1 750/4885KMT2A 1487/4885TDP1 609/4885 |
| US-20110237564-A1 | IMIDAZOPYRIMIDINE DERIVATIVES | PDE5A, PDE3B, PDE3A | MEN1 3260/4885KMT2A 2872/4885TDP1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.