Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23738732 | 0.97 | KDM4E (0.37) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23738871 | 0.88 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23739085 | 0.88 | KDM4E (0.31) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23738875 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23738770 | 0.87 | MAPT (0.35) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL23738902 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL23184331 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23184122 | 0.86 | KDM4E (0.37) | KDM4EALDH1A1HPGDTDP1NPSR1 | |
| SCHEMBL23738883 | 0.84 | CYP1A1 (0.30) | — | |
| SCHEMBL23738731 | 0.84 | SIRT2 (0.32) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388438-B1 | SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-08-11 | — | — | EP | disclosed |