Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23184331 | 0.96 | KDM4E (0.39) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL18858199 | 0.92 | KDM4E (0.39) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL23738906 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL23738875 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL23184278 | 0.85 | THRB (0.31) | — | |
| SCHEMBL23184441 | 0.85 | MAPT (0.38) | HPGDHTTNPSR1MAPTMAPK1 | |
| SCHEMBL23738732 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL23184122 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL23184248 | 0.83 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDLMNATDP1 | |
| SCHEMBL23183924 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388438-B1 | SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-08-11 | — | — | EP | disclosed |