Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NCK1 | P16333 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20880273 | 1.00 | NQO2 (0.43) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL16644141 | 0.89 | NQO2 (0.53) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL16644172 | 0.81 | NQO2 (0.46) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL24115639 | 0.80 | NQO2 (0.44) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL24115643 | 0.78 | NQO2 (0.42) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL24115709 | 0.77 | NQO2 (0.49) | NQO2KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL16639680 | 0.76 | NPC1 (0.38) | KDM4EALDH1A1MAPTTDP1RAB9A | |
| SCHEMBL24115646 | 0.75 | NPC1 (0.41) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18866930 | 0.74 | NPC1 (0.39) | KDM4EALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL19432353 | 0.73 | NQO2 (0.59) | NQO2KDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590541-B1 | DRUG-CONJUGATES AND USES THEREOF | CONCORTIS BIOSYSTEMS CORP (US) | 2021-08-11 | — | — | EP | disclosed |