Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644141 | 0.86 | NQO2 (0.53) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL16644172 | 0.79 | NQO2 (0.46) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL24115639 | 0.78 | NQO2 (0.44) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7694096 | 0.77 | NPC1 (0.50) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL20880273 | 0.77 | NQO2 (0.43) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL23739009 | 0.77 | NQO2 (0.43) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7698454 | 0.76 | NQO2 (0.45) | NQO2ALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL24115643 | 0.75 | NQO2 (0.42) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7689877 | 0.75 | SMN1; SMN2 (0.43) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL19937141 | 0.74 | MAPT (0.46) | NQO2ALDH1A1KDM4EL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925627-A1 | DRUG-CONJUGATES AND USES THEREOF | Concortis Biosystems, Corp (US) | 2021-12-22 | — | — | EP | disclosed |