Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947670 | 0.88 | RORA (0.53) | DYRK1ATLR8ALDH1A1KDM4EPGR | |
| SCHEMBL19073061 | 0.88 | PSEN1 (0.41) | DYRK1AHPGDTLR8ALDH1A1MAPT | |
| SCHEMBL12593197 | 0.86 | TLR8 (0.56) | TLR8PGRRORARORCRORB | |
| SCHEMBL12593201 | 0.85 | TLR8 (0.55) | TLR8PGRRORARORCRORB | |
| SCHEMBL12593198 | 0.85 | TLR8 (0.55) | TLR8PGRRORARORCRORB | |
| SCHEMBL13304767 | 0.83 | RORA (0.55) | HPGDTLR8ALDH1A1MAPTKDM4E | |
| SCHEMBL12548590 | 0.83 | KDM4E (0.43) | DYRK1AHPGDTLR8ALDH1A1MAPT | |
| SCHEMBL31609261 | 0.82 | TLR8 (0.34) | TLR8ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL15458667 | 0.80 | HPGD (0.61) | HPGDALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL17704935 | 0.79 | RORA (0.46) | DYRK1ATLR8ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397637-B1 | COMPOUND FOR PHOTOACTIVE ORGANIC ELECTRONIC ELEMENT, AND PHOTOACTIVE ORGANIC ELECTRONIC ELEMENT COMPRISING THE COMPOUND | HELIATEK GMBH (DE) | 2021-08-11 | — | — | EP | disclosed |