SCHEMBL2374044

SCHEMBL2374044

NC1=NC2=NC=NC2(N)C=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7530927 0.76
SCHEMBL28646765 0.60
SCHEMBL28638745 0.54
SCHEMBL4263336 0.54
SCHEMBL30476130 0.54
SCHEMBL29224558 0.54
SCHEMBL64911 0.53
SCHEMBL4440463 0.51
SCHEMBL22193800 0.48
SCHEMBL9351695 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155027-B1 SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS APPLERA CORP (US) 2003-10-01 EP claimed
US-10472408-B2 Fusion proteins comprising partial tetraspanin sequences and a system thereof for presenting peptides on the cell surface PETER UND TRAUDL ENGELHORN-STIFTUNG ZUR FÖRDERUNG DER LEBENSWISSENSCHAFTEN (DE) 2019-11-12 US disclosed
US-20190010211-A1 SYSTEM FOR PRESENTING PEPTIDES ON THE CELL SURFACE PETER UND TRAUDL ENGELHORN-STIFTUNG ZUR FÖRDERUNG DER LEBENSWISSENSCHAFTEN (DE) 2019-01-10 US disclosed
EP-1757621-B1 Compositions and methods for the treatment and diagnosis of immune disorders MILLENNIUM PHARM INC (US) 2011-09-07 EP disclosed
US-20080050393-A1 Novel nucleic acids and polypeptides NUVELO, INC. (A NEVADA CORPORATION) 2008-02-28 US disclosed
US-7001731-B2 Chemokine receptor obtained from a cDNA library of fetal liver-spleen NUVELO, INC. (US) 2006-02-21 US disclosed
US-6979548-B2 Chemokine receptor obtained from a CDNA library of fetal liver-spleen NUVELO, INC. (US) 2005-12-27 US disclosed
US-20050222393-A1 Antibody specific for a chemokine receptor; immunoassay and kits HYSEQ, INC. 2005-10-06 US disclosed
EP-1012335-A4 METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES HYSEQ INC (US) 2004-06-09 EP disclosed
US-20030187198-A1 Novel chemokine receptor obtained from a cDNA library of fetal liver-spleen HYSEQ, INC. 2003-10-02 US disclosed
US-20020042048-A1 METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES CALLIDA GENOMICS, INC. 2002-04-11 US disclosed
US-20020034737-A1 METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES HYSEQ, INC. 2002-03-21 US disclosed
US-6355419-B1 A SEQUENCING METHOD USING HYBRIDIZATION CONDITIONS THAT ARE ADJUSTED TO INCREASE HYBRIDIZATION WITH NUCLEIC ACIDS WITHIN EACH POOL USING AN ARRAY OF PROBES AFFIXED TO A SUBSTRATE COMPLEMENTARY TO THE NUCLEIC ACID SEQUENCE OF THE TARGET HYSEQ, INC. 2002-03-12 US disclosed
US-6309824-B1 ANALYZING PREFERENTIAL NUCLEOTIDE SEQUENCES; MIX NUCLEOTIDE SEQUENCES AND PROBES, INCUBATE TARGET NUCLEOTIDE SEQUENCES WITH IMMOBILIZED NUCLEOTIDE SEQUENCES, JOIN IMMOBLIZED AND LABELED PROBES, DETECT BOUND TARGET NUCLEOTIDE SEQUENCES HYSEQ, INC. 2001-10-30 US disclosed
US-6297006-B1 SEQUENCE DETERIMINATION OF TARGET NUCLEOTIDE SEQUENCES; MIX OLIGONUCLEOTIDES AND SAMPLE, HYBRIDIZE OLIGONUCLEOTIDE, LIGATE, SEPARATE LIGATED OLIGONUCLEOTIDES AND UNLIGATED OLIGONUCLEOTIDES, DETERMINE NUCLEOTIDE SEQUENCE HYSEQ, INC. 2001-10-02 US disclosed
EP-1012335-A1 METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES HYSEQ, INC. (US) 2000-06-28 EP disclosed
WO-2000000515-A2 A CHEMOKINE RECEPTOR OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN HYSEQ, INC. (US) 2000-01-06 WO disclosed
WO-1999041382-A2 A NOVEL INTERLEUKIN-3 AND USES THEREOF HYSEQ, INC. (US) 1999-08-19 WO disclosed
WO-1999036567-A2 ENHANCED DISCRIMINATION OF PERFECT MATCHES FROM MISMATCHES USING A MODIFIED DNA LIGASE HYSEQ, INC. (US) 1999-07-22 WO disclosed
WO-1999009217-A1 METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES HYSEQ, INC. (US) 1999-02-25 WO disclosed