⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712126 | 0.74 | — | — | |
| SCHEMBL7718436 | 0.64 | — | — | |
| SCHEMBL3685876 | 0.56 | — | — | |
| SCHEMBL2374044 | 0.53 | — | — | |
| SCHEMBL9774599 | 0.52 | — | — | |
| SCHEMBL2885121 | 0.52 | — | — | |
| SCHEMBL7530927 | 0.51 | — | — | |
| SCHEMBL33790 | 0.49 | — | — | |
| SCHEMBL31299889 | 0.48 | — | — | |
| SCHEMBL22193800 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 870 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2179039-B1 | RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES | ZOETIS BELGIUM S A (BE) | 2018-10-31 | — | — | EP | claimed |
| EP-2451475-A2 | SELF REPLICATING RNA MOLECULES AND USES THEREOF | Novartis AG (CH) | 2012-05-16 | — | — | EP | claimed |
| US-8128944-B2 | RNA sequence motifs in the context of defined internucleotide linkages inducing specific immune modulatory profiles | COLEY PHARMACEUTICAL GMBH (DE) | 2012-03-06 | — | — | US | claimed |
| US-20110300205-A1 | SELF REPLICATING RNA MOLECULES AND USES THEREOF | NOVARTIS AG (CH) | 2011-12-08 | — | — | US | claimed |
| WO-2011005799-A2 | SELF REPLICATING RNA MOLECULES AND USES THEREOF | NOVARTIS AG (CH) | 2011-01-13 | — | — | WO | claimed |
| US-20100272785-A1 | RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES | COLEY PHARMACEUTICAL GMBH (DE) | 2010-10-28 | — | — | US | claimed |
| EP-2179039-A2 | RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES | Coley Pharmaceuticals GmbH (DE) | 2010-04-28 | — | — | EP | claimed |
| WO-2009022216-A9 | RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES | COLEY PHARM GMBH (DE) | 2009-04-30 | — | — | WO | claimed |
| WO-2009022216-A2 | RNA SEQUENCE MOTIFS IN THE CONTEXT OF DEFINED INTERNUCLEOTIDE LINKAGES INDUCING SPECIFIC IMMUNE MODULATORY PROFILES | COLEY PHARMACEUTICAL GMBH (US) | 2009-02-19 | — | — | WO | claimed |
| WO-2008033432-A2 | IMMUNE MODULATION BY CHEMICALLY MODIFIED RIBONUCLEOSIDES AND OLIGORIBONUCLEOTIDES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-20 | — | — | WO | claimed |
| US-20060241076-A1 | Modified oligoribonucleotide analogs with enhanced immunostimulatory activity | COLEY PHARMACEUTICAL GMBH (DE) | 2006-10-26 | — | — | US | claimed |
| JP-2002523335-A | — | — | 2002-07-30 | — | — | JP | claimed |
| US-6388061-B1 | INCLUDES RUTHENIUM TRIS(BIPYRIDYL) LABEL BONDED TO THE NITROGEN BASE | DAKO A/S (DK) | 2002-05-14 | — | — | US | claimed |
| US-20010021772-A1 | SHORT OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-09-13 | — | — | US | claimed |
| EP-1102842-A2 | ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION | Aventis Pharma Deutschland GmbH (DE) | 2001-05-30 | — | — | EP | claimed |
| EP-1100894-A2 | SHORT OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION | Aventis Pharma Deutschland GmbH (DE) | 2001-05-23 | — | — | EP | claimed |
| WO-2000008141-A2 | SHORT OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-02-17 | — | — | WO | claimed |
| WO-2000008140-A2 | ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-02-17 | — | — | WO | claimed |
| EP-0979869-A1 | Short oligonucleotides for the inhibition of VEGF expression | Hoechst Marion Roussel Deutschland GmbH (DE) | 2000-02-16 | — | — | EP | claimed |
| EP-0978561-A1 | Antisense oligonucleotides for the inhibition of VEGF expression | Hoechst Marion Roussel Deutschland GmbH (DE) | 2000-02-09 | — | — | EP | claimed |