SCHEMBL2374056

SCHEMBL2374056

Nc1cc(Br)c(OCc2ccccc2)cc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.45
CTSV O60911 2/20 0.45
CTSL P07711 2/20 0.45
PIN1 Q13526 2/20 0.43
MGMT P16455 1/20 0.43
CYP19A1 P11511 4/20 0.43
PTGES O14684 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
ATM Q13315 1/20 0.41
SGMS2 Q8NHU3 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2145763 0.86 POLB (0.52) POLBMEN1KMT2AMAPTCTSV
SCHEMBL2049375 0.84 PTGES (0.54) POLBMEN1KMT2AMAPTCTSV
SCHEMBL15984738 0.84 POLB (0.48) POLBMEN1KMT2AMAPTCTSV
SCHEMBL30381370 0.83 POLB (0.49) POLBMEN1KMT2AMAPTCTSV
SCHEMBL16537734 0.83 MEN1 (0.53) POLBMEN1KMT2AMAPTCTSV
SCHEMBL7426704 0.81 PTGES (0.51) POLBMEN1KMT2AMAPTCTSV
SCHEMBL1193049 0.81 PIN1 (0.49) POLBMEN1KMT2AMAPTCTSV
SCHEMBL8316270 0.81 MEN1 (0.55) POLBMEN1KMT2AMAPTCTSV
SCHEMBL24624730 0.81 MEN1 (0.45) POLBMEN1KMT2AMAPTCTSV
SCHEMBL29923057 0.81 MEN1 (0.45) POLBMEN1KMT2AMAPTCTSV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US claimed
CN-101657921-B High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES CO US 2013-06-12 CN claimed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
EP-2135313-B1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP claimed
CN-101657921-A High-performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES CO US 2010-02-24 CN claimed
EP-2135313-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M Innovative Properties Company (US) 2009-12-23 EP claimed
WO-2008127828-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-23 WO claimed
US-9287568-B2 High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-03-15 US disclosed
CN-101657921-B High performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES CO US 2013-06-12 CN disclosed
US-20110319257-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US disclosed
EP-2135313-B1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP disclosed
CN-101657921-A High-performance, high durability non-precious metal fuel cell catalysts 3M INNOVATIVE PROPERTIES CO US 2010-02-24 CN disclosed
EP-2135313-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M Innovative Properties Company (US) 2009-12-23 EP disclosed
WO-2008127828-A1 HIGH PERFORMANCE, HIGH DURABILITY NON-PRECIOUS METAL FUEL CELL CATALYSTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-23 WO disclosed