SCHEMBL2374148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2376050	0.82	CYP3A4 (0.46)	JAK2SYKSMG1PARP1JAK1
	SCHEMBL31681826	0.82	CYP3A4 (0.46)	JAK2SYKSMG1PARP1JAK1
	SCHEMBL2376107	0.80	SMG1 (0.56)	JAK2SMG1PARP1JAK1JAK3
	SCHEMBL2375403	0.78	PLK4 (0.55)	JAK2EPHB4SMG1PARP1JAK1
	SCHEMBL31681845	0.76	SMG1 (0.51)	EGFRSYKSMG1FLT1
	SCHEMBL2375211	0.76	SMG1 (0.51)	EGFRSYKSMG1FLT1
	SCHEMBL2375410	0.76	ZAP70 (0.61)	EGFR
	SCHEMBL12231947	0.74	ZAP70 (0.49)	JAK2EGFRSYKEPHB4SMG1
	SCHEMBL30839088	0.74	JAK2 (0.64)	JAK2SYKPARP1JAK1JAK3
	SCHEMBL2374619	0.73	EGFR (0.53)	JAK2EGFRSYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.