SCHEMBL2376050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31681826	1.00	CYP3A4 (0.46)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2
	SCHEMBL2374148	0.82	JAK2 (0.56)	SYKJAK2JAK1JAK3SMG1
	SCHEMBL2376107	0.82	SMG1 (0.56)	JAK2JAK1JAK3SMG1FLT3
	SCHEMBL2375211	0.80	SMG1 (0.51)	SYKNR2C2TAB1SMG1MTOR
	SCHEMBL31681845	0.80	SMG1 (0.51)	SYKNR2C2TAB1SMG1MTOR
	SCHEMBL2375403	0.80	PLK4 (0.55)	JAK2JAK1JAK3NR2C2TAB1
	SCHEMBL2375410	0.77	ZAP70 (0.61)	IGF1R
	SCHEMBL12231947	0.75	ZAP70 (0.49)	SYKJAK2JAK1JAK3SMG1
	SCHEMBL30839088	0.75	JAK2 (0.64)	SYKJAK2JAK1JAK3FLT3
	SCHEMBL20726570	0.73	HRH4 (0.41)	CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.