Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.42 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.42 |
| ▸ | SMG1 | Q96Q15 | 5/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376050 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2374148 | 0.82 | JAK2 (0.56) | SYKJAK2JAK1JAK3SMG1 | |
| SCHEMBL2376107 | 0.82 | SMG1 (0.56) | JAK2JAK1JAK3SMG1FLT3 | |
| SCHEMBL31681845 | 0.80 | SMG1 (0.51) | SYKNR2C2TAB1SMG1MTOR | |
| SCHEMBL2375211 | 0.80 | SMG1 (0.51) | SYKNR2C2TAB1SMG1MTOR | |
| SCHEMBL2375403 | 0.80 | PLK4 (0.55) | JAK2JAK1JAK3NR2C2TAB1 | |
| SCHEMBL2375410 | 0.77 | ZAP70 (0.61) | IGF1R | |
| SCHEMBL12231947 | 0.75 | ZAP70 (0.49) | SYKJAK2JAK1JAK3SMG1 | |
| SCHEMBL30839088 | 0.75 | JAK2 (0.64) | SYKJAK2JAK1JAK3FLT3 | |
| SCHEMBL20726570 | 0.73 | HRH4 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | MCL1, BCL2, BCLAF1 | CYP3A4 4875/4885CYP2D6 4834/4885CYP2C9 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.