Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.70 |
| ▸ | AXL | P30530 | 1/20 | 0.70 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.70 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.70 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HPGDS | O60760 | 1/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | CDC25C | P30307 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605142 | 0.84 | CDC25A (0.69) | RAB9AKDM4EALDH1A1CYP19A1NPC1 | |
| SCHEMBL11460926 | 0.84 | RAB9A (0.94) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL7495850 | 0.84 | RAB9A (1.00) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL6649362 | 0.84 | CYP19A1 (0.87) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL6196239 | 0.83 | CYP19A1 (1.00) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| Hydrochloric Acid SCHEMBL11452940 | 0.82 | RAB9A (0.97) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL27676399 | 0.81 | RAB9A (0.77) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL8978641 | 0.81 | CYP19A1 (0.89) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL11473901 | 0.81 | RAB9A (0.77) | RAB9AKDM4EALDH1A1CYP19A1AXL | |
| SCHEMBL11359373 | 0.81 | CYP19A1 (0.89) | RAB9AKDM4EALDH1A1CYP19A1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | RAB9A 1418/4885KDM4E 3500/4885ALDH1A1 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.