SCHEMBL2374318

SCHEMBL2374318

CO[Si](OC)(OC)C(CCN)CCNC=CNCc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH7 P40394 1/20 0.34
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL516374 0.84 MEN1 (0.44) MAPTMEN1KMT2ATDP1
SCHEMBL4234819 0.83 HTR2A (0.32) NPC1MAPTHPGDRAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL5971835 0.83 MEN1 (0.43) MAPTMEN1KMT2ATDP1
Ethylene SCHEMBL27558649 0.82 MEN1 (0.42) MAPTMEN1KMT2ATDP1
Ethylene SCHEMBL27987258 0.81 MEN1 (0.41) MAPTMEN1KMT2ATDP1
SCHEMBL614445 0.74 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2
SCHEMBL5810206 0.74 MEN1 (0.42) MAPTSMN1; SMN2MEN1KMT2ATDP1
SCHEMBL98709 0.71 HRH1 (0.35) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL447452 0.70 ALDH1A1 (0.40) ALDH1A1
Hydrochloric Acid SCHEMBL440810 0.70 KMT2A (0.35) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023750-B2 Aqueous hydrophilizing surface treatment agent, hydrophilic coating film and hydrophilizing surface treatment method NIHON PARKERIZING CO., LTD. (JP) 2018-07-17 US disclosed
US-20150232681-A1 HYDROPHILIC SURFACE TREATMENT AGENT FOR ALUMINUM-CONTAINING METAL HEAT EXCHANGERS HAVING EXCELLENT DRAINAGE NIHON PARKERIZING CO., LTD. (JP) 2015-08-20 US disclosed
US-8304092-B2 Surface-treated galvanized steel sheet with superior flat-portion corrosion resistance, blackening resistance, and appearance and corrosion resistance after press forming and aqueous surface-treatment liquid for galvanized steel sheet JFE STEEL CORPORATION (JP) 2012-11-06 US disclosed
EP-1524332-B1 SURFACE-TREATED STEEL SHEET EXCELLENT IN RESISTANCE TO WHITE RUST AND METHOD FOR PRODUCTION THEREOF JFE STEEL CORP (JP) 2011-09-14 EP disclosed
US-20100035055-A1 Surface-treated galvanized steel sheet with superior flat-portion corrosion resistance, blackening resistance, and appearance and corrosion resistance after press forming and aqueous surface-treatment liquid for galvanized steel sheet JFE STEEL CORPORATION (JP) 2010-02-11 US disclosed
US-7291402-B2 Surface-treated steel sheets of good white rust resistance, and method for producing them JFE STEEL CORPORATION (JP) 2007-11-06 US disclosed
US-20050147832-A1 Surface-treated steel sheet excellent in resistance to white rust and method for production thereof KANSAI PAINT CO., LTD. (JP) 2005-07-07 US disclosed
EP-1524332-A1 SURFACE-TREATED STEEL SHEET EXCELLENT IN RESISTANCE TO WHITE RUST AND METHOD FOR PRODUCTION THEREOF JFE Steel Corporation (JP) 2005-04-20 EP disclosed