Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 5/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.52 |
| ▸ | CCND1 | P24385 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743167 | 0.88 | GUSB (0.75) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL23743359 | 0.85 | GUSB (0.55) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL23743213 | 0.82 | GUSB (0.63) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL16007517 | 0.74 | GUSB (1.00) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL31238611 | 0.74 | GUSB (1.00) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL17786541 | 0.72 | GUSB (0.71) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL23743266 | 0.72 | CYP1B1 (0.78) | GUSBCYP1A1CYP1B1CYP1A2KDM4E | |
| SCHEMBL874165 | 0.70 | GUSB (0.68) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL11379972 | 0.70 | GUSB (0.68) | GUSBCYP1A1CYP1B1CDK4CCND1 | |
| SCHEMBL24490603 | 0.70 | GUSB (0.71) | GUSBCYP1A1CYP1B1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | GUSB 101/4885CYP1A1 6/4885CYP1B1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.