Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 16/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 16/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 16/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.55 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.55 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743198 | 0.82 | CYP1A1 (0.51) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30587661 | 0.82 | CYP1A1 (0.69) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL23743152 | 0.81 | CYP1A1 (0.63) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL25706432 | 0.80 | CYP1A2 (1.00) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL19076267 | 0.80 | NFE2L2 (0.53) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL10423997 | 0.80 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL10423998 | 0.80 | CYP1A1 (1.00) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL19076183 | 0.76 | CYP1A2 (0.68) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL23743178 | 0.76 | CYP1A1 (0.70) | CYP1A1CYP1B1CYP1A2NFE2L2CYP3A4 | |
| SCHEMBL23743170 | 0.75 | CYP1A1 (0.67) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | CYP1A1 6/4885CYP1B1 2/4885CYP1A2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.