Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26089355 | 0.85 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL24945788 | 0.79 | GPR119 (0.35) | PTPN11 | |
| SCHEMBL11996276 | 0.74 | ACACB (0.36) | — | |
| SCHEMBL26087410 | 0.72 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL19756416 | 0.70 | ACACB (0.41) | — | |
| SCHEMBL26850081 | 0.68 | ACACB (0.35) | — | |
| SCHEMBL23744157 | 0.68 | PTPN11 (0.44) | PTPN11 | |
| SCHEMBL31492320 | 0.68 | PTPN11 (0.38) | PTPN11 | |
| SCHEMBL26790071 | 0.67 | ACACB (0.34) | — | |
| SCHEMBL26818713 | 0.67 | ACACB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |