Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diamfenetide SCHEMBL168664 | 0.92 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL12322301 | 0.91 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9795852 | 0.89 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11111056 | 0.87 | ALDH1A1 (0.80) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL12287264 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11070291 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL30693907 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL25395866 | 0.86 | KMT2A (0.71) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL10889365 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL15223764 | 0.86 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |