Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 13/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745431 | 0.97 | CCR2 (0.40) | ADAMTS5DPP4FAPCCR2 | |
| SCHEMBL29835185 | 0.83 | ADAMTS5 (0.54) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL29250233 | 0.83 | ADAMTS5 (0.54) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL29835157 | 0.79 | ADAMTS5 (0.54) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL23745405 | 0.79 | ADAMTS5 (0.54) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL23727481 | 0.77 | ADAMTS5 (0.58) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL23727483 | 0.77 | ADAMTS5 (0.58) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL29250257 | 0.75 | ADAMTS5 (0.55) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL23745214 | 0.75 | ADAMTS5 (0.55) | ADAMTS5MMP13ADAM17 | |
| SCHEMBL29835134 | 0.75 | ADAMTS5 (0.55) | ADAMTS5MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |