Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745387 | 1.00 | FAP (0.40) | FAPDPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL29835177 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL31121188 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL23745304 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL23745243 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL31121195 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL23728091 | 0.84 | ADAMTS5 (0.54) | DPP7ADAMTS5ADAM17MMP2 | |
| SCHEMBL30013242 | 0.75 | DPP7 (0.41) | FAPDPP7NAMPTDPP4CCR2 | |
| SCHEMBL30013203 | 0.75 | DPP7 (0.41) | FAPDPP7NAMPTDPP4CCR2 | |
| SCHEMBL23745323 | 0.72 | DPP7 (0.49) | FAPDPP7NAMPTDPP4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |