Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13939996 | 0.85 | DPP7 (0.51) | DPP7NAMPTTMEM97SIGMAR1ACACB | |
| SCHEMBL24826055 | 0.78 | SIGMAR1 (0.51) | NAMPTTMEM97SIGMAR1ACACBKCNH2 | |
| SCHEMBL12183955 | 0.77 | DPP7 (0.47) | DPP7NAMPTTMEM97SIGMAR1KCNH2 | |
| SCHEMBL2056192 | 0.77 | DPP7 (0.47) | DPP7NAMPTTMEM97SIGMAR1KCNH2 | |
| SCHEMBL13594616 | 0.75 | DPP7 (0.56) | DPP7NAMPTALDH1A1DPP4NOTUM | |
| SCHEMBL6369620 | 0.75 | HRH3 (0.47) | DPP7TMEM97SIGMAR1ACACBDRD2 | |
| SCHEMBL29964619 | 0.75 | ACACB (0.49) | DPP7NAMPTTMEM97SIGMAR1ACACB | |
| SCHEMBL16624019 | 0.75 | ACACB (0.52) | DPP7TMEM97SIGMAR1ACACBDRD2 | |
| SCHEMBL13923531 | 0.74 | DPP7 (0.45) | DPP7NAMPTTMEM97SIGMAR1KCNH2 | |
| SCHEMBL14528648 | 0.73 | ACACB (0.47) | DPP7ACACBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |