Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025550 | 0.86 | PKM (0.48) | HTR2CDRD2HTR2AMALT1AKR1B1 | |
| SCHEMBL27471150 | 0.83 | HTR2C (0.44) | HTR2CDRD2HTR2AMALT1AKR1B1 | |
| SCHEMBL9220704 | 0.81 | AKR1B1 (0.42) | HTR2CDRD2HTR2AMALT1AKR1B1 | |
| SCHEMBL7606467 | 0.80 | PKM (0.40) | MALT1KDM1APKMPKLRNPC1 | |
| SCHEMBL4974003 | 0.79 | ALDH1A1 (0.49) | MALT1MAPT | |
| SCHEMBL2856886 | 0.79 | AKT1 (0.43) | KDM1APKMPKLRNPC1MAPT | |
| SCHEMBL15075057 | 0.79 | MALT1 (0.46) | HTR2CMALT1KDM1APKMPKLR | |
| SCHEMBL23422992 | 0.79 | KDM1A (0.40) | HTR2CHTR2AKDM1APKMNPC1 | |
| SCHEMBL31254037 | 0.79 | ALDH1A1 (0.49) | MALT1MAPT | |
| SCHEMBL15075072 | 0.78 | TRPV1 (0.39) | HTR2CHTR2APKMPKLRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155791-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-08-12 | — | — | WO | disclosed |