Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170702 | 0.91 | HRH3 (0.56) | HRH3SMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL10077424 | 0.85 | HRH3 (0.59) | HRH3SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL18538137 | 0.84 | HRH3 (0.57) | HRH3SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL18538130 | 0.84 | HRH3 (0.57) | HRH3SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL4547887 | 0.80 | HRH3 (0.65) | HRH3SMN1; SMN2ALDH1A1NOS3NOS1 | |
| SCHEMBL25137036 | 0.79 | HRH3 (0.62) | HRH3SMN1; SMN2MEN1NPC1TP53 | |
| SCHEMBL19441606 | 0.79 | HRH3 (0.62) | HRH3SMN1; SMN2ALDH1A1NOS3NOS1 | |
| SCHEMBL19441582 | 0.79 | HRH3 (0.62) | HRH3SMN1; SMN2ALDH1A1NOS3NOS1 | |
| SCHEMBL16604254 | 0.78 | HRH3 (0.54) | HRH3SMN1; SMN2ALDH1A1NOS3NOS1 | |
| SCHEMBL25110359 | 0.78 | ALDH1A1 (0.48) | HRH3SMN1; SMN2MEN1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | AR, KLK3, BRDT | HRH3 1695/4885SMN1; SMN2 4595/4885MEN1 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.