SCHEMBL23747260

SCHEMBL23747260

CC1(C)OCC(C)(C(=O)Oc2ccc(-c3ccccc3)cc2)CO1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
LMNA P02545 3/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 3/20 0.43
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41
CYP2C19 P33261 1/20 0.41
ELANE P08246 1/20 0.39
FABP7 O15540 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848342 0.78 POLB (0.38) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL17589271 0.75 L3MBTL1 (0.50) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL18259718 0.75 L3MBTL1 (0.51) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL16153566 0.74 TTR (0.60) KMT2AMEN1SMN1; SMN2KDM4ENPC1
SCHEMBL14967776 0.74 L3MBTL1 (0.59) KMT2AMEN1TDP1SMN1; SMN2KDM4E
SCHEMBL9154171 0.73 HSD17B10 (0.71) KMT2AMEN1TDP1SMN1; SMN2NPC1
SCHEMBL1713590 0.73 HSD17B10 (0.71) KMT2AMEN1TDP1SMN1; SMN2NPC1
SCHEMBL29399270 0.73 HSD17B10 (0.71) KMT2AMEN1TDP1SMN1; SMN2NPC1
SCHEMBL20848344 0.72 POLB (0.40) KMT2AMEN1TDP1SMN1; SMN2RAB9A
SCHEMBL16143245 0.72 TTR (0.52) KMT2AMEN1SMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384287-B2 Side chain liquid crystal epoxy monomer (S-LCEM) and preparation method thereof, and side chain liquid crystal epoxy resin (S-LCER) with high intrinsic thermal conductivity NORTHWESTERN POLYTECHNICAL UNIVERSITY (CN) 2022-07-12 US disclosed
US-20210246372-A1 SIDE CHAIN LIQUID CRYSTAL EPOXY MONOMER (S-LCEM) AND PREPARATION METHOD THEREOF, AND SIDE CHAIN LIQUID CRYSTAL EPOXY RESIN (S-LCER) WITH HIGH INTRINSIC THERMAL CONDUCTIVITY NORTHWESTERN POLYTECHNICAL UNIVERSITY (CN) 2021-08-12 US disclosed