Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848344 | 0.92 | POLB (0.40) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL20848342 | 0.87 | POLB (0.38) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL20848640 | 0.82 | MAPT (0.38) | L3MBTL1POLBMAPTTDP1GAA | |
| SCHEMBL18259718 | 0.81 | L3MBTL1 (0.51) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL27890730 | 0.78 | L3MBTL1 (0.54) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL24885614 | 0.77 | ESR1 (0.39) | L3MBTL1POLBATMKDM4EALDH1A1 | |
| SCHEMBL846827 | 0.77 | ALDH1A1 (0.47) | L3MBTL1TDP1ALDH1A1KMT2A | |
| SCHEMBL14967776 | 0.76 | L3MBTL1 (0.59) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL27796546 | 0.76 | L3MBTL1 (0.48) | L3MBTL1POLBATMMAPTTDP1 | |
| SCHEMBL23747260 | 0.75 | KMT2A (0.46) | L3MBTL1POLBMAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127523-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2019-05-02 | — | — | US | disclosed |
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2018-05-17 | — | — | US | disclosed |
| US-9868821-B2 | Polymeric nanogels with degradable backbones and from gras components, and compositions and methods thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-16 | — | — | US | disclosed |
| US-9868821-B2 | Polymeric nanogels with degradable backbones and from gras components, and compositions and methods thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160075829-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075829-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | CD44, PGLS, HPSE | L3MBTL1 2783/4885POLB 3936/4885ATM 2739/4885 |
| US-20180134845-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | CD44, PGLS, HPSE | L3MBTL1 2783/4885POLB 3936/4885ATM 2739/4885 |
| US-20190127523-A1 | POLYMERIC NANOGELS WITH DEGRADABLE BACKBONES AND FROM GRAS COMPONENTS, AND COMPOSITIONS AND METHODS THEREOF | CD44, PGLS, HPSE | L3MBTL1 2783/4885POLB 3936/4885ATM 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.