Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 5/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747739 | 0.80 | LSS (0.60) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23728168 | 0.79 | ALDH1A1 (0.65) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23747629 | 0.79 | ALDH1A1 (0.65) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23747630 | 0.79 | ALDH1A1 (0.65) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23728173 | 0.76 | RAB9A (0.55) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23747548 | 0.74 | RAB9A (0.66) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23747713 | 0.74 | RAB9A (0.66) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23747596 | 0.72 | RAB9A (0.63) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23727986 | 0.72 | RAB9A (0.75) | RAB9ANPC1POLBNAMPTLSS | |
| SCHEMBL23727642 | 0.72 | RAB9A (0.75) | RAB9ANPC1POLBNAMPTLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |