Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796142 | 0.88 | PPARG (0.43) | L3MBTL1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL23747874 | 0.87 | TLR8 (0.40) | L3MBTL1PDGFRBPDGFRAMAP4K4BACE1 | |
| SCHEMBL23747866 | 0.84 | L3MBTL1 (0.37) | L3MBTL1PDGFRBPDGFRAMAP4K4MEN1 | |
| SCHEMBL18796266 | 0.81 | MAP4K4 (0.36) | MAP4K4BACE1MEN1KMT2AEGLN1 | |
| SCHEMBL23747861 | 0.79 | MAPT (0.42) | L3MBTL1HTTCYP3A4PPARGALDH1A1 | |
| SCHEMBL20506407 | 0.79 | MAOB (0.39) | L3MBTL1PDGFRBPDGFRACYP3A4PPARG | |
| SCHEMBL18796176 | 0.78 | PPARG (0.43) | L3MBTL1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL18796115 | 0.77 | EGLN1 (0.38) | MAP4K4BACE1MEN1KMT2AEGLN1 | |
| SCHEMBL18796036 | 0.74 | GAA (0.45) | L3MBTL1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL18796173 | 0.74 | GAA (0.45) | L3MBTL1PDGFRBPDGFRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | claimed |