Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ARNT | P27540 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796279 | 0.89 | ALDH1A1 (0.48) | MAPTALDH1A1GAASMN1; SMN2PIN1 | |
| SCHEMBL23747859 | 0.88 | TLR8 (0.46) | MAPTALDH1A1GAAHSPB1PIN1 | |
| SCHEMBL18796303 | 0.83 | MAPT (0.42) | MAPTALDH1A1GAAHSPB1SMN1; SMN2 | |
| SCHEMBL18795920 | 0.80 | MAPT (0.40) | MAPTALDH1A1GAAHSPB1SMN1; SMN2 | |
| SCHEMBL23747871 | 0.79 | L3MBTL1 (0.37) | ALDH1A1HTTCYP3A4PPARGHPGD | |
| SCHEMBL23747866 | 0.79 | L3MBTL1 (0.37) | MAPTALDH1A1GAAHTTCYP3A4 | |
| SCHEMBL18796268 | 0.75 | TLR8 (0.48) | MAPTALDH1A1GAAPIN1HTT | |
| SCHEMBL18796214 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1GAASMN1; SMN2PIN1 | |
| SCHEMBL18796231 | 0.74 | PIN1 (0.46) | MAPTALDH1A1GAAHSPB1SMN1; SMN2 | |
| SCHEMBL20506407 | 0.74 | MAOB (0.39) | ALDH1A1CYP3A4PPARGHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | claimed |