Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654046 | 0.81 | NAAA (0.54) | NAAAIDO1AGXTAPP | |
| SCHEMBL16685531 | 0.73 | NAAA (0.49) | NAAAALDH1A1MAPTIDO1AGXT | |
| SCHEMBL18615761 | 0.72 | NAAA (0.54) | NAAAIDO1AGXTKDM4EAPP | |
| SCHEMBL16654121 | 0.71 | NAAA (0.54) | NAAAIDO1AGXTSMN1; SMN2APP | |
| SCHEMBL22454181 | 0.70 | NAAA (0.56) | NAAAIDO1AGXTSMN1; SMN2KDM4E | |
| SCHEMBL16685958 | 0.70 | NAAA (0.49) | NAAAALDH1A1MAPTIDO1AGXT | |
| SCHEMBL28811360 | 0.70 | IDO1 (0.52) | NAAAIDO1AGXTAPP | |
| SCHEMBL11224617 | 0.69 | NAAA (0.62) | NAAAALDH1A1IDO1AGXTKMT2A | |
| SCHEMBL16685900 | 0.69 | NAAA (0.51) | NAAAIDO1AGXTAPP | |
| SCHEMBL3049685 | 0.69 | NAAA (0.58) | NAAAIDO1AGXTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550285-A1 | TRIOXACARCINS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119549-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-09-29 | — | — | WO | disclosed |