Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18475579 | 0.81 | APP (0.44) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL16654046 | 0.79 | NAAA (0.54) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL18697013 | 0.79 | IDO1 (0.42) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL15731991 | 0.77 | IDO1 (0.61) | IDO1AGXTAPPMAOBCALM1 | |
| SCHEMBL24597253 | 0.76 | IDO1 (0.50) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL18615761 | 0.76 | NAAA (0.54) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL22454181 | 0.74 | NAAA (0.56) | IDO1AGXTAPPNAAA | |
| SCHEMBL17864877 | 0.74 | CALM1 (0.41) | IDO1AGXTAPPNAAAHRH3 | |
| SCHEMBL15953973 | 0.73 | IDO1 (0.52) | IDO1AGXTAPPNAAAMAOB | |
| SCHEMBL11224617 | 0.73 | NAAA (0.62) | IDO1AGXTAPPNAAAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425742-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |