SCHEMBL23748415

SCHEMBL23748415

CCCCCCCCC([SiH3])(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
GGPS1 O95749 6/20 0.37
SMPD1 P17405 5/20 0.36
FDPS P14324 9/20 0.35
CES2 O00748 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12805505 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL6036710 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL12806189 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL29120357 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL6047731 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL4232263 1.00 TSHR (0.40) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL3655924 0.90 TSHR (0.32) TSHRTHRBFDPS
SCHEMBL537846 0.78
SCHEMBL21723155 0.78 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL29124493 0.78 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323035-A1 HYDROGENPOLYORGANOSILOXANE AND THERMALLY CONDUCTIVE SILICONE COMPOSITION THEREOF WACKER CHEMIE AG (DE) 2023-10-12 US disclosed
US-11745477-B2 Polyolefin based multilayer film with a hybrid barrier layer SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-09-05 US disclosed
EP-4211182-A1 HYDROGENPOLYORGANOSILOXANE AND THERMALLY CONDUCTIVE SILICONE COMPOSITION THEREOF Wacker Chemie AG (DE) 2023-07-19 EP disclosed
EP-3863850-B1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-06-28 EP disclosed
WO-2022047776-A1 HYDROGENPOLYORGANOSILOXANE AND THERMALLY CONDUCTIVE SILICONE COMPOSITION THEREOF WACKER CHEMIE AG (DE) 2022-03-10 WO disclosed
US-20210379874-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-09 US disclosed
EP-3863850-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC Global Technologies B.V. (NL) 2021-08-18 EP disclosed
CN-113165325-A Polyolefin-based multilayer film with hybrid barrier layer SABIC环球技术有限责任公司 2021-07-23 CN disclosed