Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.36 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12805505 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6036710 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL12806189 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL29120357 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6047731 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL23748415 | 1.00 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL3655924 | 0.90 | TSHR (0.32) | TSHRTHRBFDPS | |
| SCHEMBL537846 | 0.78 | — | — | |
| SCHEMBL21723155 | 0.78 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL29124493 | 0.78 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326097-A1 | SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF | NISSAN MOTOR CO., LTD. | 2009-12-31 | — | — | US | disclosed |
| EP-2048189-A1 | SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF | Nissan Motor Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |