SCHEMBL23748425

SCHEMBL23748425

C#C[C@@]1(O)[C@@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.71
ADORA3 P0DMS8 4/20 0.57
PI4KA P42356 2/20 0.57
PI4K2B Q8TCG2 2/20 0.57
PI4K2A Q9BTU6 2/20 0.57
PI4KB Q9UBF8 2/20 0.57
DPP4 P27487 1/20 0.57
MEN1 O00255 1/20 0.57
SLC28A1 O00337 1/20 0.57
MAP3K7 O43318 1/20 0.57
SLC28A2 O43868 1/20 0.57
GAPDH P04406 1/20 0.57
MAPK1 P28482 1/20 0.57
ADORA2B P29275 1/20 0.57
ADORA1 P30542 1/20 0.57
STAT6 P42226 1/20 0.57
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
DOT1L Q8TEK3 1/20 0.57
SLC29A1 Q99808 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18874985 1.00 ADORA2A (0.71) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL9395400 1.00 ADORA2A (0.71) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL29722607 1.00 ADORA2A (0.71) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL9395384 1.00 ADORA2A (0.71) ADORA2AADORA3PI4KAPI4K2BPI4K2A
Phosphoric Acid SCHEMBL21489151 0.95 ADORA2A (0.65) ADORA2AADORA3PI4KAPI4K2BPI4K2A
Phosphoric Acid SCHEMBL21465116 0.95 ADORA2A (0.65) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL31725339 0.89 ADORA2A (0.62) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL3437115 0.88 ADORA2A (0.54) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1374258 0.86 ADORA2A (0.67) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1374261 0.86 ADORA2A (0.67) ADORA2AADORA3PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 US claimed
WO-2021224646-A1 METHOD FOR THE TREATMENT OF RNA VIRUS INVOLVED DISEASES TURNSOLE BIOLOGICS LLC. (HU) 2021-11-11 WO claimed
US-20210330808-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-10-28 US claimed
EP-3863609-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2021-08-18 EP claimed
CN-112823000-A Small polymer carriers for agent delivery 联邦高等教育系统匹兹堡大学 2021-05-18 CN claimed
US-12466849-B2 Anti-viral and anti-tumoral compounds YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-11-11 US disclosed
US-20250281574-A1 COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS OF VIRAL INFECTIONS AND OTHER RESPIRATORY DISORDERS XEQUEL BIO INC (US) 2025-09-11 US disclosed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
US-20250161334-A1 Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient PEYMAN GHOLAM A (US) 2025-05-22 US disclosed
US-20250057975-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2025-02-20 US disclosed
US-12226478-B2 Method of treating, reducing, or alleviating a medical condition in a patient PEYMAN GHOLAM A (US) 2025-02-18 US disclosed
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 US disclosed
US-20230072222-A1 ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS YEDA RESEARCH AND DEVELOPMENT CO. LTD (IL) 2023-03-09 US disclosed
WO-2022165386-A1 LNP AND LMP DELIVERY OF ANTIVIRAL NUCLEOTIDE 5'-PHOSPHATES VIRBIS LLC (US) 2022-08-04 WO disclosed
US-20220202933-A1 Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient PEYMAN GHOLAM A (US) 2022-06-30 US disclosed
WO-2022038539-A2 ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-02-24 WO disclosed
WO-2021224646-A1 METHOD FOR THE TREATMENT OF RNA VIRUS INVOLVED DISEASES TURNSOLE BIOLOGICS LLC. (HU) 2021-11-11 WO disclosed
US-20210330808-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-10-28 US disclosed
EP-3863609-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2021-08-18 EP disclosed
CN-112823000-A Small polymer carriers for agent delivery 联邦高等教育系统匹兹堡大学 2021-05-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230072222-A1 ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS EIF2AK2, NSUN2, SARS1 ADORA2A 3677/4885ADORA3 4073/4885PI4KA 1552/4885
US-12466849-B2 Anti-viral and anti-tumoral compounds EIF2AK2, NSUN2, SARS1 ADORA2A 3677/4885ADORA3 4073/4885PI4KA 1552/4885
US-20250057975-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS CD44, PGF, SLC46A1 ADORA2A 3965/4885ADORA3 4137/4885PI4KA 2734/4885
US-12083185-B2 Small polymeric carriers for delivery of agents CD44, PGF, SLC46A1 ADORA2A 3965/4885ADORA3 4137/4885PI4KA 2734/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 ADORA2A 2769/4885ADORA3 4081/4885PI4KA 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.