Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240989 | 0.86 | PLA2G1B (0.38) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL388153 | 0.86 | PLA2G1B (0.38) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL8953223 | 0.80 | LMNA (0.39) | DNM1PLA2G1BPLA2G2A | |
| SCHEMBL8953430 | 0.80 | LMNA (0.39) | DNM1PLA2G1BPLA2G2A | |
| SCHEMBL7075098 | 0.79 | MAPT (0.31) | — | |
| SCHEMBL2419404 | 0.78 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL10685373 | 0.78 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL9514238 | 0.78 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL4618599 | 0.78 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1 | |
| SCHEMBL8773201 | 0.78 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864002-B1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-12-27 | — | — | EP | disclosed |
| US-20220033345-A1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2022-02-03 | — | — | US | disclosed |
| EP-3864002-A1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | 3M Innovative Properties Company (US) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033345-A1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | PARP1, ETFA, PARP2 | DNM1 414/4885PLA2G1B 1029/4885PLA2G2A 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.