⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599392 | 0.77 | GLP1R (0.40) | — | |
| SCHEMBL28952286 | 0.77 | GLP1R (0.40) | — | |
| SCHEMBL24276781 | 0.74 | — | — | |
| SCHEMBL31323121 | 0.71 | GLP1R (0.39) | — | |
| SCHEMBL25045565 | 0.69 | THRB (0.33) | — | |
| SCHEMBL31692185 | 0.68 | GLP1R (0.36) | — | |
| SCHEMBL31323116 | 0.68 | GLP1R (0.38) | — | |
| SCHEMBL24599387 | 0.66 | — | — | |
| SCHEMBL31323144 | 0.64 | GLP1R (0.40) | — | |
| SCHEMBL31424397 | 0.64 | GLP1R (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155841-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |