SCHEMBL23748629

SCHEMBL23748629

CC/C=C\CCCCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP24A1 Q07973 2/20 0.39
LPAR2 Q9HBW0 3/20 0.39
LPAR3 Q9UBY5 3/20 0.39
LPAR1 Q92633 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
PSMD10 O75832 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
G6PD P11413 1/20 0.37
STAT3 P40763 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30821470 0.97 ALDH1A1 (0.40) CYP24A1LPAR2LPAR3LPAR1CA12
SCHEMBL10731427 0.96 ALDH1A1 (0.43) CYP24A1LPAR2LPAR3LPAR1ALDH1A1
SCHEMBL15237138 0.95 CYP24A1 (0.40) CYP24A1CA12CA1CA9PSMD10
SCHEMBL7268342 0.95 CYP24A1 (0.40) CYP24A1CA12CA1CA9PSMD10
SCHEMBL13491291 0.93 ADORA3 (0.43) CYP24A1CA12CA1CA9PSMD10
SCHEMBL1914559 0.90 MCHR1 (0.43) CA12CA1CA9TSHR
SCHEMBL1914562 0.90 MCHR1 (0.43) CA12CA1CA9TSHR
SCHEMBL10730061 0.90 MCHR1 (0.43) CA12CA1CA9TSHR
SCHEMBL10730052 0.90 MCHR1 (0.43) CA12CA1CA9TSHR
SCHEMBL15912664 0.89 CA12 (0.40) CYP24A1CA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864001-A1 ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-08-18 EP disclosed
CN-113166024-A Aromatic compounds and their medical use 巴斯夫股份公司 2021-07-23 CN disclosed