Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.78 |
| ▸ | CA9 | Q16790 | 6/20 | 0.78 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336990 | 0.87 | CA12 (1.00) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL9490269 | 0.86 | CA12 (0.97) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL9490703 | 0.86 | CA12 (0.97) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL10766816 | 0.86 | CA12 (0.97) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL9309072 | 0.80 | RECQL (0.62) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL617098 | 0.79 | CA12 (0.79) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL23748711 | 0.79 | CA12 (0.51) | CA12CA9TSHREPHX2SMN1; SMN2 | |
| Hexane SCHEMBL27656302 | 0.77 | TSHR (0.50) | CA12CA9RECQLMEN1TSHR | |
| SCHEMBL11177092 | 0.77 | AKR1C3 (0.57) | CA12CA9MEN1KMT2ATP53 | |
| SCHEMBL3701389 | 0.77 | CA12 (0.56) | CA12CA9RECQLMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864001-A1 | ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-08-18 | — | — | EP | disclosed |