SCHEMBL3701389

SCHEMBL3701389

CCCCNS(=O)(=O)c1cccc(C)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA9 Q16790 3/20 0.56
RECQL P46063 1/20 0.54
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2C19 P33261 2/20 0.52
TSHR P16473 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 5/20 0.48
POLB P06746 2/20 0.46
BRD4 O60885 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
ALOX12 P18054 1/20 0.44
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9309072 0.94 RECQL (0.62) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL9230028 0.90 CA12 (0.54) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL31391062 0.87 CA12 (0.63) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL635553 0.87 CA12 (0.63) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL5178084 0.84 CA12 (0.57) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL9228164 0.83 ALDH1A1 (0.50) CA12CA9MEN1KMT2AALDH1A1
SCHEMBL635207 0.82 RECQL (0.68) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL8355313 0.81 RECQL (0.70) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL634179 0.81 RECQL (0.70) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL223155 0.81 RECQL (0.70) CA12CA9RECQLCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US claimed
US-20120118616-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POLYIMIDE RESIN FILM USING SAME, AND FLEXIBLE PRINTED CIRCUIT BOARD SUMITOMO ELECTRIC PRINTED CIRCUITS, INC. (JP) 2012-05-17 US disclosed
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US disclosed