SCHEMBL28039136

SCHEMBL28039136

CCCCCCCCCCNc1cccc(C(=O)OC(C)(C)C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.44
CNR1 P21554 1/20 0.44
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
NAAA Q02083 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
EPHX2 P34913 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28039144 1.00 CNR2 (0.44) CNR2CNR1ADRA1AADRA1BPDK1
SCHEMBL28823422 1.00 CNR2 (0.44) CNR2CNR1ADRA1AADRA1BPDK1
SCHEMBL28038888 1.00 CNR2 (0.44) CNR2CNR1ADRA1AADRA1BPDK1
SCHEMBL28038832 0.95 ADRA1A (0.42) CNR2CNR1ADRA1AADRA1BTSHR
SCHEMBL31665348 0.87 NAMPT (0.44) ADRA1AADRA1BALDH1A1L3MBTL1KDM4E
SCHEMBL31110129 0.87 NAMPT (0.44) ADRA1AADRA1BALDH1A1L3MBTL1KDM4E
SCHEMBL23748672 0.85 KDM4E (0.52) CNR2CNR1ALDH1A1LMNAKDM4E
SCHEMBL5136114 0.81 PLK1 (0.51) CNR2CNR1PLK1
SCHEMBL23748664 0.80 CNR2 (0.50) CNR2CNR1ALDH1A1KDM4EPLK1
SCHEMBL28038899 0.77 ADRA1A (0.42) ADRA1AADRA1BALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104981249-A Antimicrobial compounds, their synthesis and applications thereof SEC DEP FOR HEALTH 2015-10-14 CN disclosed