Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23748612 | 0.85 | PLA2G2A (0.56) | TSHRTP53PLA2G2A | |
| SCHEMBL5090283 | 0.84 | PLA2G2A (0.59) | TSHRTP53PLA2G2A | |
| SCHEMBL5095051 | 0.84 | PLA2G2A (0.59) | TSHRTP53PLA2G2A | |
| SCHEMBL11049569 | 0.84 | PLA2G2A (0.59) | TSHRTP53PLA2G2A | |
| SCHEMBL11333568 | 0.80 | TSHR (0.59) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL14440035 | 0.79 | TSHR (0.60) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11337110 | 0.78 | TSHR (0.56) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL14091969 | 0.78 | PLA2G2A (0.51) | TSHRTP53ESR1PLA2G2A | |
| SCHEMBL23748659 | 0.77 | ALDH1A1 (0.68) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL18417204 | 0.76 | TSHR (0.65) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473249-B2 | Aromatic compounds and pharmaceutical uses thereof | BASF AS (NO) | 2025-11-18 | — | — | US | disclosed |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| EP-3864001-A1 | ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473249-B2 | Aromatic compounds and pharmaceutical uses thereof | GLS2, FFAR3, SLC10A1 | TSHR 1202/4885TP53 2379/4885CYP3A4 132/4885 |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | GLS2, FFAR3, SLC10A1 | TSHR 1202/4885TP53 2379/4885CYP3A4 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.