Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723622 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALPLMAPK1TDP1HTT | |
| SCHEMBL30132070 | 0.82 | ALDH1A1 (0.57) | ALDH1A1ALPLMAPK1TDP1HTT | |
| SCHEMBL23749875 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALPLMAPK1TDP1TP53 | |
| SCHEMBL23723683 | 0.78 | HTT (0.57) | ALDH1A1ALPLMAPK1TDP1TP53 | |
| SCHEMBL26526228 | 0.73 | ALDH1A1 (0.54) | ALDH1A1ALPLMAPK1TDP1HTT | |
| SCHEMBL23723730 | 0.73 | ALDH1A1 (0.56) | ALDH1A1ALPLMAPK1TDP1TP53 | |
| SCHEMBL26523253 | 0.70 | HTT (0.55) | ALDH1A1ALPLMAPK1TDP1TP53 | |
| SCHEMBL30132103 | 0.69 | ALDH1A1 (0.58) | ALDH1A1ALPLTDP1ALOX15TSHR | |
| SCHEMBL23723554 | 0.69 | ALDH1A1 (0.58) | ALDH1A1ALPLTDP1ALOX15TSHR | |
| SCHEMBL23723536 | 0.66 | TDP1 (0.61) | ALDH1A1ALPLMAPK1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021156774-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2021-08-12 | — | — | WO | disclosed |