Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723622 | 1.00 | ALDH1A1 (0.57) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL26526228 | 0.90 | ALDH1A1 (0.54) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL23749876 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL30132103 | 0.79 | ALDH1A1 (0.58) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL23723554 | 0.79 | ALDH1A1 (0.58) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL23723519 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL23723730 | 0.77 | ALDH1A1 (0.56) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL23723548 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ALPLHTTKDM4ELMNA | |
| SCHEMBL23723545 | 0.73 | RXFP1 (0.46) | ALDH1A1ALPLHTTRXFP1KDM4E | |
| SCHEMBL4213024 | 0.71 | HTT (0.68) | ALDH1A1HTTRXFP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |