Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750267 | 1.00 | GABBR2 (0.51) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750264 | 0.85 | GABBR2 (0.54) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750265 | 0.85 | GABBR2 (0.54) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750253 | 0.84 | PRMT6 (0.39) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750251 | 0.84 | PRMT6 (0.39) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750203 | 0.84 | GABBR2 (0.47) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750127 | 0.84 | GABBR2 (0.47) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL24879115 | 0.83 | GABBR2 (0.51) | GABBR2GABBR1RXRARXRBRXRG | |
| SCHEMBL23750382 | 0.82 | GABBR2 (0.46) | GABBR2GABBR1GAAAOC3 | |
| SCHEMBL23750223 | 0.82 | GABBR2 (0.46) | GABBR2GABBR1GAAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246169-A1 | COMPOUNDS | SPERO THERAPEUTICS, INC. (US) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246169-A1 | COMPOUNDS | MRPS18A, MRPL37, MRPS35 | GABBR2 4179/4885GABBR1 4092/4885RXRA 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.