Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | XDH | P47989 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584559 | 0.88 | POLB (0.78) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL21584535 | 0.88 | POLB (0.78) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL21584455 | 0.88 | POLB (0.78) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL23015432 | 0.88 | POLB (0.78) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL13090372 | 0.88 | POLB (0.78) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL23750586 | 0.87 | POLB (0.77) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL12793495 | 0.86 | LMNA (0.69) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL23750582 | 0.86 | POLB (0.60) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL21729793 | 0.83 | GAA (0.50) | POLBXDHL3MBTL1KDM4ELMNA | |
| SCHEMBL21584376 | 0.82 | POLB (0.73) | POLBXDHL3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155864-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-08-12 | — | — | WO | disclosed |