Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | XDH | P47989 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750514 | 0.86 | POLB (0.60) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL16900476 | 0.84 | LMNA (0.61) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL21729793 | 0.83 | GAA (0.50) | LMNAKDM4EXDHTDP1POLB | |
| Gallic Acid Methyl Ester SCHEMBL39513 | 0.82 | KDM4E (1.00) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL17297683 | 0.81 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| Gallic Acid Methyl Ester SCHEMBL21611341 | 0.81 | KDM4E (0.95) | LMNAKDM4EXDHTDP1POLB | |
| Gallic Acid Methyl Ester SCHEMBL21543905 | 0.81 | KDM4E (0.95) | LMNAKDM4EXDHTDP1POLB | |
| Gallic Acid Methyl Ester SCHEMBL28507408 | 0.81 | KDM4E (0.95) | LMNAKDM4EXDHTDP1POLB | |
| Gallic Acid Methyl Ester SCHEMBL28556619 | 0.81 | KDM4E (0.95) | LMNAKDM4EXDHTDP1POLB | |
| SCHEMBL6430785 | 0.79 | CA5A (0.45) | LMNAKDM4EXDHTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017108978-A1 | PASSION FLOWER SEED EXTRACT, AND COSMETIC, PHARMACEUTICAL OR DERMATOLOGICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES EXPANSCIENCE (FR) | 2017-06-29 | — | — | WO | disclosed |
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | ORX PHARMACEUTICAL CORPORATION (CA) | 2015-09-03 | — | — | US | disclosed |
| US-9061993-B2 | Derivatives of propane diyl dicinnamate | Toronto Institute of Pharmaceutical Technology (CA) | 2015-06-23 | — | — | US | disclosed |
| US-20110086912-A1 | Derivatives of Propane Diyl Dicinnamate | MACGREGOR ALEXANDER | 2011-04-14 | — | — | US | disclosed |
| US-20090236229-A1 | METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DECR2, DECR1 | LMNA 3051/4885KDM4E 1830/4885XDH 3363/4885 |
| US-20110086912-A1 | Derivatives of Propane Diyl Dicinnamate | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DECR2, DECR1 | LMNA 3050/4885KDM4E 1786/4885XDH 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.