Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741253 | 0.80 | MEN1 (0.76) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21568080 | 0.80 | NPC1 (0.67) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11048619 | 0.80 | MEN1 (0.76) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2095180 | 0.78 | NPC1 (0.64) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1507740 | 0.78 | NPC1 (0.64) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3912100 | 0.78 | NPC1 (0.64) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31325146 | 0.77 | ALDH1A1 (0.64) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15691175 | 0.76 | NPC1 (0.61) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23752424 | 0.76 | MEN1 (0.61) | NPC1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22674771 | 0.76 | SMN1; SMN2 (0.67) | NPC1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |