SCHEMBL23752147

SCHEMBL23752147

OC(=S)Nc1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 1/20 0.61
MAPT P10636 3/20 0.59
KDM4E B2RXH2 1/20 0.59
NPC1 O15118 4/20 0.53
ALDH1A1 P00352 3/20 0.53
RAB9A P51151 3/20 0.53
GAA P10253 1/20 0.53
EPHX1 P07099 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CNR1 P21554 1/20 0.52
NPSR1 Q6W5P4 2/20 0.52
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5445907 0.82 MAPT (0.75) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL8956455 0.82 MAPT (0.75) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL5081276 0.79 NOX1 (0.85) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL8956349 0.79 NOX1 (0.85) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL10189868 0.78 EPHX1 (0.60) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL11018889 0.78 MAPT (0.57) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL27885438 0.78 MAPT (0.57) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL526059 0.78 MAPT (0.63) NOX1MAPTKDM4ENPC1ALDH1A1
SCHEMBL10977035 0.76 MAPT (0.55) NOX1MAPTKDM4ENPC1ALDH1A1
Thiourea SCHEMBL1991944 0.76 MAPT (0.73) NOX1MAPTKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
CN-1254281-A HIV and cancer treatment PROCTER & GAMBLE (US) 2000-05-24 CN disclosed